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Multistage analysis method for detection of effective herb prescription from clinical data

null

《医学前沿(英文)》 2018年 第12卷 第2期   页码 206-217 doi: 10.1007/s11684-017-0525-8

摘要:

Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated personalized manifestations in real-world patients and the individualized combination therapies prescribed in clinical settings. In this study, a multistage analysis method that integrates propensity case matching, complex network analysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions for particular diseases (e.g., insomnia). First, propensity case matching was applied to match clinical cases. Then, core network extraction and herb set enrichment were combined to detect core effective herb prescriptions. Effectiveness-based mutual information was used to detect strong herb–symptom relationships. This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational studies. Results revealed that groups of herb prescriptions with higher effectiveness rates (76.9% vs. 42.8% for matched samples; 94.2% vs. 84.9% for all samples) compared with the original prescriptions were found. Particular patient groups with symptom manifestations were also identified to help investigate the indications of the effective herb prescriptions.

关键词: effective prescription detection     herb set enrichment analysis     core network extraction     insomnia     personalized treatment    

Predicting the yield of pomegranate oil from supercritical extraction using artificial neural networksand an adaptive-network-based fuzzy inference system

J. Sargolzaei, A. Hedayati Moghaddam

《化学科学与工程前沿(英文)》 2013年 第7卷 第3期   页码 357-365 doi: 10.1007/s11705-013-1336-3

摘要: Various simulation tools were used to develop an effective intelligent system to predict the effects of temperature and pressure on an oil extraction yield. Pomegranate oil was extracted using a supercritical CO (SC-CO ) process. Several simulation systems including a back-propagation neural network (BPNN), a radial basis function neural network (RBFNN) and an adaptive-network-based fuzzy inference system (ANFIS) were tested and their results were compared to determine the best predictive model. The performance of these networks was evaluated using the coefficient of determination ( ) and the mean square error (MSE). The best correlation between the predicted and the experimental data was achieved using the BPNN method with an of 0.9948.

关键词: oil recovery     artificial intelligence     extraction     neural networks     supercritical extraction    

Entity and relation extraction with rule-guided dictionary as domain knowledge

《工程管理前沿(英文)》   页码 610-622 doi: 10.1007/s42524-022-0226-0

摘要: Entity and relation extraction is an indispensable part of domain knowledge graph construction, which can serve relevant knowledge needs in a specific domain, such as providing support for product research, sales, risk control, and domain hotspot analysis. The existing entity and relation extraction methods that depend on pretrained models have shown promising performance on open datasets. However, the performance of these methods degrades when they face domain-specific datasets. Entity extraction models treat characters as basic semantic units while ignoring known character dependency in specific domains. Relation extraction is based on the hypothesis that the relations hidden in sentences are unified, thereby neglecting that relations may be diverse in different entity tuples. To address the problems above, this paper first introduced prior knowledge composed of domain dictionaries to enhance characters’ dependence. Second, domain rules were built to eliminate noise in entity relations and promote potential entity relation extraction. Finally, experiments were designed to verify the effectiveness of our proposed methods. Experimental results on two domains, including laser industry and unmanned ship, showed the superiority of our methods. The F1 value on laser industry entity, unmanned ship entity, laser industry relation, and unmanned ship relation datasets is improved by +1%, +6%, +2%, and +1%, respectively. In addition, the extraction accuracy of entity relation triplet reaches 83% and 76% on laser industry entity pair and unmanned ship entity pair datasets, respectively.

关键词: entity extraction     relation extraction     prior knowledge     domain rule    

An extraction- assay system: Evaluation on flavonols in plant resistance to Pb and Cd by supercriticalextraction- gas chromatography

Xu Zhang, Huanhuan Yang, Xinlei Wang, Wen Song, Zhaojie Cui

《环境科学与工程前沿(英文)》 2018年 第12卷 第4期 doi: 10.1007/s11783-018-1059-2

摘要:

SFE-GC system is established for flavonols assessment.

Optimal parameters of SFE-GC are evaluated and determined.

Quercetin and kaempferol are detected in plant under heavy metal stress.

Gene expression analysis shows consistent regularity with content of flavonols.

ROS level is applied for elaborating the plant resistance status.

关键词: Flavonols     Heavy metal     Supercritical carbon dioxide extraction (SFE)     GC     Plant resistance    

Postprocessor development for ultrasonic cutting of honeycomb core curved surface with a straight blade

《机械工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0729-8

摘要: When ultrasonically cutting honeycomb core curved parts, the tool face of the straight blade must be along the curved surface’s tangent direction at all times to ensure high-quality machining of the curved surface. However, given that the straight blade is a nonstandard tool, the existing computer-aided manufacturing technology cannot directly realize the above action requirement. To solve this problem, this paper proposed an algorithm for extracting a straight blade real-time tool face vector from a 5-axis milling automatically programmed tool location file, which can realize the tool location point and tool axis vector conversion from the flat end mill to the straight blade. At the same time, for the multi-solution problem of the rotation axis, the dependent axis rotation minimization algorithm was introduced, and the spindle rotation algorithm was proposed for the tool edge orientation problem when the straight blade is used to machine the curved part. Finally, on the basis of the MATLAB platform, the dependent axis rotation minimization algorithm and spindle rotation algorithm were integrated and compiled, and the straight blade ultrasonic cutting honeycomb core postprocessor was then developed. The model of the machine tool and the definition of the straight blade were conducted in the VERICUT simulation software, and the simulation machining of the equivalent entity of the honeycomb core can then be realized. The correctness of the numerical control program generated by the postprocessor was verified by machining and accuracy testing of the two designed features. Observation and analysis of the simulation and experiment indicate that the tool pose is the same under each working condition, and the workpieces obtained by machining also meet the corresponding accuracy requirements. Therefore, the postprocessor developed in this paper can be well adapted to the honeycomb core ultrasonic cutting machine tool and realize high-quality and high-efficient machining of honeycomb core composites.

关键词: honeycomb core     straight blade     ultrasonic cutting     tool pose     postprocessor    

Feature extraction from slice data for reverse engineering

ZHANG Yingjie, LU Shangning

《机械工程前沿(英文)》 2007年 第2卷 第1期   页码 25-31 doi: 10.1007/s11465-007-0004-z

摘要: A new approach to feature extraction for slice data points is presented. The reconstruction of objects is performed as follows. First, all contours in each slice are extracted by contour tracing algorithms. Then the data points on the contours are analyzed, and the curve segments of the contours are divided into three categories: straight lines, conic curves and B-spline curves. The curve fitting methods are applied for each curve segment to remove the unwanted points with pre-determined tolerance. Finally, the features, which consist of the object and connection relations among them, are founded by matching the corresponding contours in adjacent slices, and 3D models are reconstructed based on the features. The proposed approach has been implemented in OpenGL, and the feasibility of the proposed method has been verified by several cases.

关键词: feasibility     corresponding     B-spline     pre-determined tolerance     extraction    

A microextraction approach for rapid extraction and separation of Mn(II) and Co(II) using saponified

《化学科学与工程前沿(英文)》 2022年 第16卷 第6期   页码 963-972 doi: 10.1007/s11705-021-2081-7

摘要: In this paper, we proposed a microextraction approach for the extraction and separation of Mn(II) and Co(II) from sulfate solution simulating leachate of spent lithium-ion battery cathode materials using saponified di-(2-ethylhexyl)phosphoric acid system. The effects of the following operational variables were investigated: equilibrium pH, tri-n-butyl phosphate concentration, saponification rate, two-phase ratio and residence time. The results showcased that the microextractor can reach the extraction equilibrium within 20 s, thereby greatly reducing necessary extraction time comparing to that of conventional processes. The volumetric mass transfer coefficient showed 8–21 times larger than that of batch device. With the help of microextractor, 95% of Mn(II) was extracted with a single theoretical stage at a chosen two-phase ratio of 3:1, and the separation factor βMn/Co was as large as 65.5. In the subsequent stripping step, more than 99% of manganese from loaded phase was easily stripped under optimal conditions. The microextraction approach greatly enhances the mass transfer while enabling a continuous and controllable extraction process within a simple structure design. When extracting spent electrode material with microextractors, the comprehensive recovery of mangenese can reach 96%. The microextraction approach has a good applicability in the spent lithium-ion battery cathode materials recycling at both bench and industrial scales.

关键词: extraction equilibrium     mass transfer coefficient     microextraction     multicomponent extraction     di-(2-ethylhexyl)phosphoric acid    

Performance evaluation of an improved biomass-fired cogeneration system simultaneously using extraction

《能源前沿(英文)》 2022年 第16卷 第2期   页码 321-335 doi: 10.1007/s11708-021-0741-4

摘要: An advanced cogeneration system based on biomass direct combustion was developed and its feasibility was demonstrated. In place of the traditional single heat source (extraction steam), the extraction steam from the turbine, the cooling water from the plant condenser, and the low-pressure feedwater from the feedwater preheating system were collectively used for producing district heat in the new scheme. Hence, a remarkable energy-saving effect could be achieved, improving the overall efficiency of the cogeneration system. The thermodynamic and economic performance of the novel system was examined when taking a 35 MW biomass-fired cogeneration unit for case study. Once the biomass feed rate and net thermal production remain constant, an increment of 1.36 MW can be expected in the net electric production, because of the recommended upgrading. Consequently, the total system efficiency and effective electrical efficiency augmented by 1.23 and 1.50 percentage points. The inherent mechanism of performance enhancement was investigated from the energy and exergy aspects. The economic study indicates that the dynamic payback period of the retrofitting project is merely 1.20 years, with a net present value of 5796.0 k$. In conclusion, the proposed concept is validated to be advantageous and profitable.

关键词: biomass-fired cogeneration     district heat production system     absorption heat pump     extraction steam     cooling water     low-pressure feedwater    

Establishment and verification of a shrinking core model for dilute acid hydrolysis of lignocellulose

Cunwen WANG, Xiaoling DUAN, Weiguo WANG, Zihao LI, Yuanhang QIN

《能源前沿(英文)》 2012年 第6卷 第4期   页码 413-419 doi: 10.1007/s11708-012-0212-z

摘要: The kinetics of lignocellulose hydrolysis under the conditions of high temperature and dilute acid (mass fraction 0.05%) was investigated in this paper. By studying the reducing sugar concentration versus reaction temperature (170°C–220°C) and reaction time (150–1800 s) during the hydrolysis process of five kinds of crop straw (rice, wheat, cotton, rape and corn), the shrinking core model was established, and the differential equation of the model and its analytical solution were obtained. With a numerical calculation method, the kinetic equation was estimated, and the degradation of reducing sugar obeyed first-order kinetics was obtained. The calculated results from the equations agreed well with the original experimental data. The calculation by the model showed that the reducing sugar concentration increases as the size of the particles decrease, and the uniform particles increase.

关键词: lignocellulose     dilute acid hydrolysis     shrinking core model    

Study of an artificial boundary condition based on the damping-solvent extraction method

Qiang XU, Jianyun CHEN, Jing LI, Mingming WANG

《结构与土木工程前沿(英文)》 2012年 第6卷 第3期   页码 281-287 doi: 10.1007/s11709-012-0167-5

摘要: A new artificial boundary condition for time domain analysis of a structure-unlimited-foundation system was proposed. The boundary condition was based on the damping-solvent extraction method. The principle of the damping-solvent extraction method was described. An artificial boundary condition was then established by setting two spring-damper systems and one artificial damping limited region. A test example was developed to verify that the proposed boundary condition and model had high precision. Compared with the damping-solvent extraction method, this boundary condition is easier to be applied to finite element method (FEM)-based numerical calculations.

关键词: damping-solvent extraction method     structure-unlimited-foundation system     spring-damper system     artificial damping limited region     finite element method    

基于硬件加速的移动核心网实时预处理系统 Article

Mian CHENG, Jin-shu SU, Jing XU

《信息与电子工程前沿(英文)》 2017年 第18卷 第11期   页码 1720-1731 doi: 10.1631/FITEE.1700507

摘要: 随着用作通信终端或平台的移动设备越来越多,电信基础设施安全受到的威胁日益严重。作为一种移动核心网关的旁路设备,网络探测工具可以收集和分析所有经过网关的数据流量,并进行安全检测。但随着核心网链路带宽的不断提高,如何有效降低安全检测系统的处理压力是一项重要挑战。在本文中,我们设计并评估了一个由硬件加速器和多核处理器构成的报文实时预处理系统,能够快速恢复移动核心网链路中每个封装和压缩的数据包,并有效地将还原后的流量分配到多个后端安全检测系统。使用大量真实数据对系统进行测试,结果表明,我们的预处理系统可以处理所有类型的通信协议报文,并实现至少18 Gb/s的处理速率。

关键词: 移动核心网;实时报文处理;硬件加速    

Recent advances in gold-metal oxide core-shell nanoparticles: Synthesis, characterization, and their

Michelle Lukosi,Huiyuan Zhu,Sheng Dai

《化学科学与工程前沿(英文)》 2016年 第10卷 第1期   页码 39-56 doi: 10.1007/s11705-015-1551-1

摘要: Heterogeneous catalysis with core-shell structures has been a large area of focus for many years. This paper reviews the most recent work and research in core-shell catalysts utilizing noble metals, specifically gold, as the core within a metal oxide shell. The advantage of the core-shell structure lies in its capacity to retain catalytic activity under thermal and mechanical stress, which is a pivotal consideration when synthesizing any catalyst. This framework is particularly useful for gold nanoparticles in protecting them from sintering so that they retain their size, structure, and most importantly their catalytic efficiency. The different methods of synthesizing such a structure have been compiled into three categories: seed-mediated growth, post selective oxidation treatment, and one-pot chemical synthesis. The selective oxidation of carbon monoxide and reduction of nitrogen containing compounds, such as nitrophenol and nitrostyrene, have been studied over the past few years to evaluate the functionality and stability of the core-shell catalysts. Different factors that could influence the catalyst’s performance are the size, structure, choice of metal oxide shell and noble metal core and thereby the interfacial synergy and lattice mismatch between the core and shell. In addition, the morphology of the shell also plays a critical role, including its porosity, density, and thickness. This review covers the synthesis and characterization of gold-metal oxide core-shell structures, as well as how they are utilized as catalysts for carbon monoxide (CO) oxidation and selective reduction of nitrogen-containing compounds.

关键词: core-shell     characterization     core-shell structure     Different     stability    

Study on the microwave-assisted extraction of polyphenols from tea

Liyun WANG, Peiyong QIN, Yan HU,

《化学科学与工程前沿(英文)》 2010年 第4卷 第3期   页码 307-313 doi: 10.1007/s11705-009-0282-6

摘要: This study demonstrated a promising method for quickly extracting tea polyphenol (TP) by microwave-assisted extraction (MAE) technology. Some influential parameters, including MAE temperature, microwave power, concentration of extraction solvent, MAE time and the solid/liquid ratio, were investigated. The optimum condition of MAE was obtained by dual extraction with 60% ethanol (v/v) and the solid/liquid ratio 1:12 g/mL at 80°C for 10 minutes under the microwave power 600 W. The yield of TP was 96.5% under the described condition. Compared with traditional methods, including hot reflux extraction (HRE), ultrasound-assisted extraction (UAE) and supercritical fluid extraction (SFE), the extraction time was saved 8 times than that of HRE, and the yield was increased by 17.5%. The extraction time at comparable levels of production was saved 2 times, and the energy consumption was one fourth that of UAE. The extraction time was saved 5 times than that of SFE, and the yield of TP was increased by 40%. Moreover, compared with MAE of TP studied by others, it decreased the solid/liquid ratio from 1 ∶ 20 to 1 ∶ 12 g/mL without 90-min pre-leaching time, and the yield of TP was increased by 6%–40%.

关键词: energy consumption     microwave-assisted extraction     optimum condition     pre-leaching     concentration    

Oxidation-extraction desulfurization of model oil over Zr-ZSM-5/SBA-15 and kinetic study

Chuanzhu LU,Hui FU,Huipeng LI,Hua ZHAO,Tianfeng CAI

《化学科学与工程前沿(英文)》 2014年 第8卷 第2期   页码 203-211 doi: 10.1007/s11705-014-1420-3

摘要: ZSM-5/SBA-15 composite molecular sieves were synthesized using post-synthesis method and characterized by X-ray diffraction and N adsorption-desorption. The oxidative-extration desulfurization of model oil was investigated by using hydrogen peroxide as the oxidant, tetrabutyl ammonium bromide as phase transfer catalyst, dimethyl sulfoxide as extractant, and Zr-ZSM-5/SBA-15, Ag-ZSM-5/SBA-15, Ce-ZSM-5/SBA-15 as catalyst. Under the optimal conditions, the desulfurization rate decreases in the order: Zr-ZSM-5/SBA-15>Ce-ZSM-5/SBA-15>Ag-ZSM-5/SBA-15. The highest desulfurization rate is 84.53% under the catalysis of Zr-ZSM-5/SBA-15. Kinetics analysis shows that the reaction is pseudo-first-order with the activation energy of 44.23 kJ/mol.

关键词: composite molecular sieve     oxidation desulfuration     extraction     kinetic    

Extraction of hydrogen chloride by a coupled reaction-solvent extraction process

Yunzhao Li,Xingfu Song,Guilan Chen,Shuying Sun,Yanxia Xu,Jianguo Yu

《化学科学与工程前沿(英文)》 2015年 第9卷 第4期   页码 479-487 doi: 10.1007/s11705-015-1512-8

摘要: A coupled reaction-solvent extraction process was used to remove HCl from a simulated distiller waste. The extraction performances of various extractants and diluents were compared and the apparent basicity of N235 (a mixture of tertiary amines) in various diluents was determined. The best results were obtained using N235 and isoamyl alcohol as the extractant and diluent, respectively. The yield of HCl from the coupled extraction was 75% with this extraction system. The mechanisms for the removal of HCl in both the direct and coupled extractions were investigated. For the coupled extraction, the formation of an R NHCl ion-pair complex was involved in the HCl removal. For the direct extraction, the mechanism involved the formation of hydrogen bonds at high concentrations of HCl.

关键词: hydrogen chloride     distiller waste     coupled reaction and solvent extraction     N235     extraction mechanism    

标题 作者 时间 类型 操作

Multistage analysis method for detection of effective herb prescription from clinical data

null

期刊论文

Predicting the yield of pomegranate oil from supercritical extraction using artificial neural networksand an adaptive-network-based fuzzy inference system

J. Sargolzaei, A. Hedayati Moghaddam

期刊论文

Entity and relation extraction with rule-guided dictionary as domain knowledge

期刊论文

An extraction- assay system: Evaluation on flavonols in plant resistance to Pb and Cd by supercriticalextraction- gas chromatography

Xu Zhang, Huanhuan Yang, Xinlei Wang, Wen Song, Zhaojie Cui

期刊论文

Postprocessor development for ultrasonic cutting of honeycomb core curved surface with a straight blade

期刊论文

Feature extraction from slice data for reverse engineering

ZHANG Yingjie, LU Shangning

期刊论文

A microextraction approach for rapid extraction and separation of Mn(II) and Co(II) using saponified

期刊论文

Performance evaluation of an improved biomass-fired cogeneration system simultaneously using extraction

期刊论文

Establishment and verification of a shrinking core model for dilute acid hydrolysis of lignocellulose

Cunwen WANG, Xiaoling DUAN, Weiguo WANG, Zihao LI, Yuanhang QIN

期刊论文

Study of an artificial boundary condition based on the damping-solvent extraction method

Qiang XU, Jianyun CHEN, Jing LI, Mingming WANG

期刊论文

基于硬件加速的移动核心网实时预处理系统

Mian CHENG, Jin-shu SU, Jing XU

期刊论文

Recent advances in gold-metal oxide core-shell nanoparticles: Synthesis, characterization, and their

Michelle Lukosi,Huiyuan Zhu,Sheng Dai

期刊论文

Study on the microwave-assisted extraction of polyphenols from tea

Liyun WANG, Peiyong QIN, Yan HU,

期刊论文

Oxidation-extraction desulfurization of model oil over Zr-ZSM-5/SBA-15 and kinetic study

Chuanzhu LU,Hui FU,Huipeng LI,Hua ZHAO,Tianfeng CAI

期刊论文

Extraction of hydrogen chloride by a coupled reaction-solvent extraction process

Yunzhao Li,Xingfu Song,Guilan Chen,Shuying Sun,Yanxia Xu,Jianguo Yu

期刊论文